Background: FOXA2 is a member of the forkhead box family of DNA-binding proteins. FOXA2 is a hepatocyte nuclear factor (specifically, HNF-3b) that is a transcriptional activator for liver-specific genes such as albumin. During embryonic development, FOXA2 expression is a marker for cells of the definitive (but not primitive) endoderm lineage.

Immunogen: Recombinant full-length human FOXA2 expressed in E. coli and refolded to soluble form.

Purification: Protein G chromatography

Formulation: 1 mg/ml in PBS; Preservative: 0.09% NaN3

Storage: Store at 4ºC (<3 months) or -20ºC. Avoid multiple freeze-thaws.

Recommended Uses:
Western Blot 1:1000
ELISA (detect) 1:1000
Note: Optimal concentrations should be empirically determined.

Target Alternative Names: forkhead box A2; hepatic nuclear factor-3-beta; HNF3b; MGC19807; TCF3B

Target Size: 457 residues; 48.3 kDa

Target Database Links:
RefSeq Protein NP_068556
RefSeq Gene NM_021784
UniProt Q9Y261