FOXA1 Recombinant Protein

Description

FOXA1 is a member of the forkhead box family of DNA-binding proteins. FOXA1 is a hepatocyte nuclear factor (specifically, HNF-3α) that is a transcriptional activator for liver-specific genes such as AFP and albumin. During embryonic development, FoxA1 is involved in the development of multiple endoderm-derived organs such as liver, pancreas, lung and prostate. In studying in vitro stem cell differentiation, FOXA1 expression is used as a marker for endoderm lineage cells.

Source: Human
Tested Applications: SDS-PAGE, ELISA
Sequence: Full length
Tag(s): none

Size: 20 µg

Description: Recombinant full-length human FOXA1 protein

Expression:
Recombinant protein was expressed in E. coli and refolded to soluble form.

Formulation:
200 µg/ml (determined by Bradford assay) in 500 mM L-arginine, 300 mM guanidine-HCl, 50 mM HEPES, 5 mM cystamine, 5 mM cysteamine, 5 mM CaCl2,
3 mM DTT, pH 7.5
Preservative: none

Purity: >80% by SDS-PAGE

Storage: Store at -80 °C.
Avoid multiple freeze-thaws.

Alternative Names:
HNF3A; TCF3A; Hepatocyte nuclear factor 3, alpha; Forkhead box protein A1

Size: 472 AA; 49.1 kDa

Database Links:
RefSeq Protein NP_004487.2
RefSeq mRNA NM_004496.2
UniProt P55317

Warranty
Each Lot has been verified to meet quality specifications in accordance with testing guidelines. We will replace the product if it does not conform to specifications. Product guaranteed for 6 months from date of purchase if stored as directed. This product must not be resold without written permission from Primorigen Biosciences.

S2108-20UG

S2108