Recombinant human Oncostatin M expressed in engineered human cells. OSM is a 30 kDa monomeric glycoprotein and belongs to the IL-6-like protein family. OSM is a growth regulator for human fibroblasts and vascular smooth muscle cells. OSM induces the differentiation of megakaryocytes and is important in bone formation and wound healing. OSM synergizes antiproliferative effects with IFN-gamma and TGF-beta. OSM induces G-CSF and GM-CSF expression.