Pax6 Recombinant Protein

Description

Pax6 is the best described member of the paired box (Pax) family of genes encoding tissue-specific transcription factors. The Pax6 protein contains paired box and homeobox domains with DNA-binding activities, and a Pro/Ser/Thr-rich C-terminal domain with transactivation function. Pax6 is a transcription regulator important in the development of the eyes and other sensory organs, the nervous system, and other homologous tissues derived from the ectoderm. Pancreatic development also depends on Pax6, and Pax6 is used as a marker for pancreatic endoderm when inducing differentiation of stem cells.

Source: Human
Tested Applications: SDS-PAGE, WB, ELISA
Sequence: Amino acids 1-209
Epitope tag(s): none

Size: 20 µg

Description: Recombinant human Pax6 fragment (AA 1-209)

Expression:
Expressed in E. coli and purified using IMAC column purification.

Formulation:
500 µg/ml (determined by A280) in hs-PBS (1.5 mM KH2PO4, 8.1 mM Na2HPO4, 500 mM NaCl, 2.7 mM KCl, pH 7.4)
Preservative: none

Purity: >90% by SDS-PAGE

Storage: Store at -80 °C.
Avoid multiple freeze-thaws.

Alternative Names:
Paired box protein Pax-6; AN2; Oculorhombin; Aniridia type II protein

Size: 22.8 kDa (AA 1-209).
Full length Pax6 = 46.7 kDa (AA 1-422)

Database Links:
RefSeq Protein NP_000271.1
RefSeq Gene NM_000280.2
UniProt P26367

Warranty:

Each Lot has been verified to meet quality specifications in accordance with testing guidelines. We will replace the product if it does not conform to specifications. Product guaranteed for 6 months from date of purchase if stored as directed. This product must not be resold without written permission from Primorigen Biosciences.

S2114-20UG

S2114